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2B or not 2B, that is the question: further investigations into the use of pencil as a matrix for matrix-assisted laser desorption/ionisation

By G.J. Langley, J.M. Herniman and M.S. Townell

Abstract

The effective use of pencil as a matrix for matrix-assisted laser desorption/ionisation (MALDI) for the study of actinides has previously been demonstrated (Black et al., Rapid Commun. Mass Spectrom. 2006; 20: 1053). Here, the scope of the types of molecules amenable to analysis by this method has been extended, establishing that 90% of a library containing 50 diverse small molecules can be successfully analysed by this technique. Further, the role played by the bulk materials present in the different pencil leads has been investigated and a simple one-step deposition of matrix and calibration materials has been achieved through the fabrication of different calibration pencils (Cali-Pens

Topics: Q1, QD
Year: 2007
OAI identifier: oai:eprints.soton.ac.uk:44150
Provided by: e-Prints Soton

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Citations

  1. (2002). A
  2. (2006). Rapid Commun. Mass Spectrom.
  3. (1990). The Pencil: A History of Design and Circumstance.

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