Article thumbnail

Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

By Hilary Ranson, Raphael N’Guessan, Jonathan Lines, Nicolas Moiroux, Zinga Nkuni and Vincent Corbel

Abstract

Malaria remains one of the leading health problems of the developing world, and Uganda bears a particularly large burden from the disease. Our understanding is limited by a lack of reliable data, but it is clear that the prevalence of malaria infection, incidence of disease, and mortality from severe malaria all remain very high. Uganda has made progress in implementing key malaria control measures, in particular distribution of insecticide-impregnated bednets, indoor residual spraying of insecticides, utilization of artemisinin-based combination therapy to treat uncomplicated malaria, and provision of intermittent preventive therapy for pregnant women. However, despite enthusiasm regarding the potential for the elimination of malaria in other areas, there is no convincing evidence that the burden of malaria has decreased in Uganda in recent years. Major challenges to malaria control in Uganda include very high malaria transmission intensity, inadequate health care resources, a weak health system, inadequate understanding of malaria epidemiology and the impact of control interventions, increasing resistance of parasites to drugs and of mosquitoes to insecticides, inappropriate case management, inadequate utilization of drugs to prevent malaria, and inadequate epidemic preparedness and response. Despite these challenges, prospects for the control of malaria have improved, and with attention to underlying challenges, progress toward the control of malaria in Uganda can be expected

Topics: qw_45, qw_700, qx_510, qx_515, qx_650, wa_240, wc_750
Publisher: 'Elsevier BV'
Year: 2011
DOI identifier: 10.1016/j.pt.2010.08.004
OAI identifier: oai:archive.lstmed.ac.uk:2270
Provided by: LSTM Online Archive
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles