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Facile convergent route to indoloquinolines

By Kadam H.K., Malik D.D., Salgaonkar L., Mandrekar K. and Tilve S.G.


A convergent route to indoloquinolines is developed through aldol condensation. This two-step method utilizes commercially available 2-oxoindole and o-nitrobenzaldehyde as starting materials. Chromatography-free method is accomplished for preparing several derivatives of indoloquinolines with desirable aromatic substitutions on indole as well as quinoline ring. © 2017 Taylor & Francis

Topics: Aldol reaction, indoloquinoline, natural product, oxoindole, synthesis
Publisher: 'Informa UK Limited'
Year: 2020
DOI identifier: 10.1080/00397911.2017.1359303
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