Article thumbnail

Polymerasekettenreaktion-gestützte Erregerdiagnostik in der Rheumatologie

By B. Ehrenstein and U. Reischl

Abstract

In the differential diagnostics of autoimmune-mediated rheumatic diseases, rheumatologists often have to consider infections (e. g. Lyme arthritis) or reactive diseases (e. g. reactive arthritis after urogenital bacterial infections). Furthermore, infections with an atypical presentation or caused by atypical pathogens (opportunistic infections) can complicate the immunosuppressive therapy of autoimmune diseases. For this purpose not only conventional microbiological culture methods but also PCR-based methods are increasingly being applied for the direct detection of pathogens in clinical specimens. The aim of this overview is to present commonly used PCR methods in the clinical practice of rheumatology and to describe their benefits and limitations compared to culture-based detection methods

Topics: 610 Medizin, ddc:610
Publisher: 'Springer Science and Business Media LLC'
Year: 2016
DOI identifier: 10.1007/s00393-016-0058-6
OAI identifier: oai:epub.uni-regensburg.de:42230
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • https://epub.uni-regensburg.de... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.