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In vitro antifungal susceptibility profiles of 12 antifungal drugs against 55 Trichophyton schoenleinii isolates from tinea capitis favosa patients in Iran, Turkey, and China

By Deng S., Ansari S., Ilkit M., Rafati H., Hedayati M.T., Taghizadeh-Armaki M. and Nasrollahi-Omran A.


PubMedID: 27956429Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii isolates collected over the last 30 years from Iran, Turkey, and China to 12 antifungals using the CLSI broth microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independently of the geographic regions where strains were isolated. Copyright © 2017 American Society for Microbiology. All Rights Reserved.Astellas Pharma US Gilead Sciences Merck Sharp and Dohme: MSD, F2G Pfizer Astellas Pharma Global Development Gilead SciencesS.S. has received a research grant from Astellas Pharma B.V. P.E.V. has received research grants from Gilead Sciences, Astellas, Merck Sharp and Dohme (MSD), F2G, and Bio-Rad, is a speaker for Gilead Sciences and MSD, and is on the advisory boards for Pfizer, MSD, and F2G. All other authors have no conflicts of interest

Topics: Antifungal susceptibility testing, Tinea capitis favosa, Trichophyton schoenleinii
Publisher: American Society for Microbiology
Year: 2017
DOI identifier: 10.1128/AAC.01753-16
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