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A serological investigation of rotavirus infections in a shanty town population in Rio de Janeiro Investigação sorológica de infecção por rotavirus em favela do Rio de Janeiro

By Rozete Silveira Azeredo, José Paulo Gagliardi Leite, Hélio Gelli Pereira, Mirían Noemi Vidal, Fritz Sutmoller, Yves Maurice and Hermann Gonçalves Schatzmayr

Abstract

The presence of antibodies against rotavirus was investigated by enzyme immunosorbent assay (ELISA) in two distinct groups of children living in a shanty town in Rio de Janeiro. One hundred and thirty six plasma samples were randomly collected from children of 0 to 33 months (first group) and 255 serum samples were collected from other 85 children at ages of 2, 6 and 9 months (second group). A high percentage of antibodies were found in the newborn children and this rate decreased progressively until the age of 11 months, after which it increased again. At the age of 7 months, geometric mean antibody titers increased indicating that infection had occurred.<br>Cento e trinta e seis plasmas coletados aleatoriamente de crianças entre 0 e 33 meses (primeiro grupo) residentes na favela de Manguinhos, Rio de Janeiro, RJ, e 255 soros coletados de 85 crianças aos 2, 6 e 9 meses de idade (segundo grupo), residentes na mesma área, foram analisados para a presença de anticorpos (classe IgG) para rotavirus por ELISA. Anticorpos foram detectados em alto percentual de crianças recém-nascidas, declinando até o 11° mês. Elevação dos anticorpos foi observada a partir do 12° mês de vida, mas houve evidências de infecção a partir do 7° mês

Topics: ELISA, Serology, Rotavirus, LCC:Medicine (General), LCC:R5-920, LCC:Medicine, LCC:R, DOAJ:Medicine (General), DOAJ:Health Sciences
Publisher: Instituto de Medicina Tropical
Year: 1989
DOI identifier: 10.1590/S0036-46651989000400009
OAI identifier: oai:doaj.org/article:29f8616db38a4d15b35a6db235ff1b9e
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