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Deciphering the role of autophagy and exosomes in human lymphoma

By Aikaterini Kalantidou, Anna-Aspasia Karkavitsa, Georgia Orfanoudaki, Dimitra Mavridou, Aikaterini Pitsikali, Laxmikanth Kollipara, Albert Sickmann, George Rassidakis, Elias Drakos, Konstantina Psatha and Michalis Aivaliotis

Abstract

The orchestrated homeostatic action of autophagy and exosome biogenesis provides a potential causal relation with lymphomagenesis. This study aims to characterize the differently expressed proteins associated with both above-mentioned pathways, as well as to explore their potential implication in therapeutic response controlling lymphomagenesis via N3a-induced re-activated p53 in different lymphoma subtypes

Topics: , lymphoma; Nutlin-3a; proteomics; autophagy; exosomes
Publisher: Aristotle Biomedical Journal
Year: 2019
OAI identifier: oai:ejournals.lib.auth.gr:article/6884

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