(1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride

Abstract

The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two molecules in the unit cell with similar conformations. The crystal structure is stabilized by intermolecular O—H...Cl and N—H...Cl hydrogen bonds