The results of surgical treatment of metastatic liver tumor


Background: The aim of our study was to analyze the survival of patients who were operated from liver metastases. This paper is a retrospective study of the case reports from the Clinic for Operative Oncology - Oncology Institute of Vojvodina. The study included all the patients treated operatively for secondary malignant liver tumors in the period from May 2003 to May 2007. Methods: The study included 33 patients (17 men and 16 women). The mean age of patients was 57.8 years (range, 27-75 years). In 23 patients, (69.7%) metastases were of colorectal origin, while in 10 patients (30.3%) metastases originated from some other organs. Results: Hepatectomies were performed in 54.54% and metastasectomies in 45.45% of patients. More severe postoperative complications (which required repeated surgery) were registered in 3.03% of patients. Intraoperative mortality was 3.03% and postoperative mortality was 12.12%. Liver re-resection was performed in 21.21% of patients. An overall one-year survival was 75.76%, and a tree-year survival was 43.75%. One-year survival in patients with colorectal metastases was 86.96% and three-year survival was 50%, while in patients with metastases originating from some other organs, one-year survival was 70% and three-year survival was only 25%. Intrahospital mortality in patients with colorectal metastases was 8.7% while in patients with non-colorectal metastases it was 30%. Conclusion: The aim of this paper was to show that only surgical removal of metastases can lead to life quality improvement and to prolongation of the overall survival and that modern neoadjuvant and biological therapies may increase resectability of the inoperable changes

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oai:doaj.org/article:8e9f5a47418d40a4879d0b9691238430Last time updated on 12/17/2014

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