Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats

S. K. Quinney; R. E. Galinsky; V. A. Jiyamapa-Serna; Y. Chen; M. A. Hamman; S. D. Hall; R. E. Kimura

10.1124/dmd.108.020644

Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats

Authors: S. K. Quinney
R. E. Galinsky
V. A. Jiyamapa-Serna
Y. Chen
M. A. Hamman
S. D. Hall
R. E. Kimura
Publication date: 2008
Publisher: American Society for Pharmacology & Experimental Therapeutics (ASPET)

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