APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts
Abstract
10.1371/journal.pmed.1002254PLoS Medicine143e100225- Article
- apolipoprotein E
- ApoE protein, human
- apolipoprotein E
- aged
- Alzheimer disease
- APOE gene
- Article
- clinical trial (topic)
- cohort analysis
- computer model
- dementia
- female
- genetic association study
- genetic counseling
- genetic risk
- genome-wide association study
- human
- major clinical study
- male
- mild cognitive impairment
- multicenter study
- prevention study
- telephone interview
- Cognitive Dysfunction
- dementia
- gene frequency
- genetics
- genotype
- metabolism
- middle aged
- Netherlands
- risk factor
- United States
- Aged
- Apolipoproteins E
- Cognitive Dysfunction
- Cohort Studies
- Dementia
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Middle Aged
- Netherlands
- Risk Factors
- United States