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Evaluation of chikungunya diagnostic assays: Differences in sensitivity of serology assays in two independent outbreaks

By Yap G., Pok K.-Y., Lai Y.-L., Hapuarachchi H.-C., Chow A., Leo Y.-S., Tan L.-K. and Ng L.-C.

Abstract

10.1371/journal.pntd.0000753PLoS Neglected Tropical Diseases47e75

Topics: immunoglobulin M, diagnostic agent, immunoglobulin M, virus antibody, virus antigen, virus envelope protein, virus RNA, antigen detection, article, chikungunya, Chikungunya alphavirus, clinical article, controlled study, enzyme linked immunosorbent assay, human, intermethod comparison, molecular probe, nonhuman, real time polymerase chain reaction, reverse transcription polymerase chain reaction, sensitivity analysis, sensitivity and specificity, serology, Alphavirus infection, amino acid substitution, blood, Chikungunya alphavirus, comparative study, epidemic, evaluation, genetics, immunoassay, immunology, methodology, point mutation, polymerase chain reaction, Singapore, virology, Alphavirus Infections, Amino Acid Substitution, Antibodies, Viral, Antigens, Viral, Chikungunya virus, Disease Outbreaks, Humans, Immunoassay, Immunoglobulin M, Point Mutation, Polymerase Chain Reaction, RNA, Viral, Sensitivity and Specificity, Singapore, Viral Envelope Proteins, Virology
Publisher: 'Public Library of Science (PLoS)'
Year: 2010
DOI identifier: 10.1371/journal.pntd.0000753
OAI identifier: oai:scholarbank.nus.edu.sg:10635/161660
Provided by: ScholarBank@NUS
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