Skip to main content
Article thumbnail
Location of Repository

Relationship between trait anxiety, prefrontal cortex, and attention bias to angry faces in children and adolescents

By Eva H. Telzer, Karin Mogg, Brendan P. Bradley, Xiaoqin Mai, Monique Ernst, Daniel S. Pine and Christopher S. Monk


Using event-related functional magnetic resonance imaging (fMRI) with a visual-probe task that<br/>assesses attention to threat, we investigated the cognitive and neurophysiological correlates of trait<br/>anxiety in youth. During fMRI acquisition, 16 healthy children and adolescents viewed angry-neutral<br/>face pairs and responded to a probe that was on the same (angry-congruent) or opposite (angryincongruent)<br/>side as the angry face. Attention bias scores were calculated by subtracting participants’<br/>mean reaction time for angry-congruent trials from angry-incongruent trials. Trait anxiety was<br/>positively associated with attention bias towards angry faces. Neurophysiologically, trait anxiety was<br/>positively associated with right dorsolateral prefrontal cortex (PFC) activation on a contrast of trials<br/>that reflect the attention bias for angry faces (i.e., angry-incongruent versus angry-congruent trials).<br/>Trait anxiety was also positively associated with right ventrolateral PFC activation on trials with face<br/>stimuli (versus baseline), irrespective of their emotional content

Topics: BF
Year: 2008
OAI identifier:
Provided by: e-Prints Soton
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.