Using event-related functional magnetic resonance imaging (fMRI) with a visual-probe task that<br/>assesses attention to threat, we investigated the cognitive and neurophysiological correlates of trait<br/>anxiety in youth. During fMRI acquisition, 16 healthy children and adolescents viewed angry-neutral<br/>face pairs and responded to a probe that was on the same (angry-congruent) or opposite (angryincongruent)<br/>side as the angry face. Attention bias scores were calculated by subtracting participants’<br/>mean reaction time for angry-congruent trials from angry-incongruent trials. Trait anxiety was<br/>positively associated with attention bias towards angry faces. Neurophysiologically, trait anxiety was<br/>positively associated with right dorsolateral prefrontal cortex (PFC) activation on a contrast of trials<br/>that reflect the attention bias for angry faces (i.e., angry-incongruent versus angry-congruent trials).<br/>Trait anxiety was also positively associated with right ventrolateral PFC activation on trials with face<br/>stimuli (versus baseline), irrespective of their emotional content
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