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Synthetic biology

By Ali Tavassoli

Abstract

There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is expected to lead to the facile assembly of artificial biological components and integrated systems that enable innovative approaches to solving a wide range of societal challenges. Here we discuss the current state of the art and outline the next wave of synthetic biology: integrating individual components into systems

Topics: QD
Year: 2010
OAI identifier: oai:eprints.soton.ac.uk:158661
Provided by: e-Prints Soton

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  1. A fast, robust and tunable synthetic gene oscillator, doi
  2. A giant step towards artificial life?, doi
  3. (2005). A synthetic gene-metabolic oscillator, Nature, doi
  4. (2000). A synthetic oscillatory network of transcriptional regulators,
  5. (2009). A tunable synthetic mammalian oscillator, Nature, doi
  6. (2002). Chemical synthesis of poliovirus cDNA:generationofinfectiousvirusintheabsenceofnaturaltemplate, Science,
  7. (2008). Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome, Science, doi
  8. (2000). Construction of a genetic toggle switch in Escherichia coli, Nature,
  9. (1982). Cytoplasmic inclusion bodies in Escherichia coli producing biosynthetic human insulin proteins, Science, doi
  10. (2009). Diversity-based, model-guided construction of synthetic gene networks with predicted functions, doi
  11. (2006). Emergent properties of reduced-genome Escherichia coli, Science,
  12. Engineering Escherichia coli for production of functionalized terpenoids using plant P450s, doi
  13. (2008). Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli, doi
  14. (2003). Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides, doi
  15. (2007). Genome transplantation in bacteria: changing one species to another, Science, doi
  16. (2006). High-level production of amorpha-4,11-diene in a two-phase partitioning bioreactor of metabolically engineered Escherichia coli, doi
  17. (2008). Hutchison III, One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome, doi
  18. (1974). In vivo and in vitro initiation of transcription, doi
  19. (2007). M.S.Garfinkel,D.Endy,G.L.EpsteinandR.M.Friedman,Synthetic genomics | options for governance, doi
  20. (2008). Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol, M i c r o b .C e l lF a c t . , doi
  21. (2006). Miniaturising the laboratory in emulsion droplets, Trends Biotechnol., doi
  22. (1992). On the Conversion of Dihydroartemisinic Acid into doi
  23. (2006). P.L.Luisi,F.FerriandP.Stano,Approachestosemi-syntheticminimal cells: a review, Naturwissenschaften,
  24. (2006). Production of the antimalarial drug precursor artemisinic acid in engineered yeast, Nature, doi
  25. (2006). Synthetic biology: new engineering rules for an emerging discipline, doi
  26. (2009). Synthetic gene networks that count, Science, doi
  27. (1983). Total Synthesis of Qinghaosu, doi
  28. (2006). Towards synthesis of a minimal cell, doi

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