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Short Communication EVIDENCE FOR THE HYDROLYSIS OF TOPICAL APPLIED

By Liposomal Lipids, In Human and Stratum Corneum

Abstract

Abstract: Liposomes were incubated with an extract of human plantar stratum corneum. The liposomal lipids were hydrolysed, if composed of soy-bean phosphatidylcholine or phosphatidylglycerol. Rigid lipids were not degraded. The temperature optimum of the hydrolysis was between 30-35°C. CaCl2 enhanced, while EDTA reduced the rate of hydrolysis, indicating that the hydrolysis is due to a phospholipase A2

Topics: Key Words, Stratum Corneum, Liposomes, Phospholipase
Year: 2014
OAI identifier: oai:CiteSeerX.psu:10.1.1.417.1556
Provided by: CiteSeerX
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