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Analysis of the Heart Rate Variability and Stratification of the Risk of Cardiac Patients with Chagas ’ Disease

By M Vizcardo, J Jiménez, F Moleiro, A Marcano, A Octavio and A Rodríguez


According to the World wide Organization of the Health[1], the number of people infected with the Tripanosoma Cruzi is considered between 16 and 18 million, causal agent of the Chagas ’ disease, and in 100 million the people exposed to the affectation risk. When concluding in 1983 a study longitudinal epidemiologist in patients with the disease evaluated [2, 3] every 3 years, the cardiac affectation: chronic Chagasic myocarditis (MCHC) increased from a 17 % at the beginning of the study to a 49, 4 % after 15 years. Previous studies of the variability of cardiac frequency in patients with the Chagas’ disease[4, 5], show alterations in the spectral indices of the HRV. We analyze the 24-hour heart rate by Holter recordings in 62 patients with ECG alterations (CH2), 32 patients without ECG alterations (CH1) who had positive serological findings for disease of Chagas ’ and 36 healthy subjects (Control) matched for sex and age. We find a orthogonal base that is able to discriminate the groups from circadian profiles, Control and CH2, and stratify the groups CH1. 1

Year: 2014
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