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Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics

By Christina Forstner, Johannes Leitgeb, Rupert Schuster, Verena Dosch, Axel Kramer, Keith F. Cutting, David J. Leaper and Ojan Assadian

Abstract

Abstract: A flexible methacrylate powder dressing (Altrazeal ® ) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics. The antimicrobial efficacy and influence on bacterial growth kinetics in combination with three antiseptics was investigated in an in vitro porcine wound model. Standardized in vitro wounds were contaminated with Staphylococcus aureus (MRSA; ATCC 33591) and divided int

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.412.2077
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