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Review The Staphylococcus aureus RNome and Its Commitment

By To Virulence, Brice Felden, François V and Pascale Romby

Abstract

Abstract: Staphylococcus aureus is a major human pathogen causing a wide spectrum of nosocomial and community-associated infections with high morbidity and mortality. S. aureus generates a large number of virulence factors whose timing and expression levels are precisely tuned by regulatory proteins and RNAs. The aptitude of bacteria to use RNAs to rapidly modify gene expression, including virulence factors in response to stress or environmental changes, and to survive in a host is an evolving concept. Here, we focus on the recently inventoried S. aureus regulatory RNAs, with emphasis on those with identified functions, two of which are directly involved in pathogenicity

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.372.9223
Provided by: CiteSeerX
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