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By Estelle Rage, Valérie Siroux, Nino Künzli, Isabelle Pin, Francine Kauffmann and Inserm U

Abstract

Objectives- There is evidence that exposure to air pollution affects asthma, but the effect of air pollution on asthma severity has not been addressed. The aim was to assess the relation between asthma severity during the past 12 months and home outdoor concentrations of air pollution. Methods- Asthma severity over the last 12 months was assessed in two complementary ways among 328 adult asthmatics from the French Epidemiological study on the Genetics and Environment of Asthma (EGEA) examined between 1991 and 1995. The 4-class severity score integrated clinical events and type of treatment. The 5-level asthma score is based only on the occurrence of symptoms. Nitrogen dioxide (NO2), sulphur dioxide (SO2) and ozone (O3) concentrations were assigned to each residence using two different methods. The first was based on the closest monitor data from 1991-1995. The second consisted in spatial models that used geostatistical interpolations and then assigned air pollutants to the geo-coded residences (1998). Results- Higher asthma severity score was significantly related to the 8-hour average o

Topics: air pollution, asthma severity, ozone. WORD COUNT, 4441
Year: 2009
OAI identifier: oai:CiteSeerX.psu:10.1.1.371.2576
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