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Efecto de extractos de membrana de bartonella bacilliformis sobre la mitosis de linfocitos T de cavia porcellus

By María Begogna Angulo Cruzado

Abstract

Evaluar el efecto de extractos de membrana de Bartonella bacilliformis sobre la mitosis de linfocitos de Cavia porcellus. Metodología: Se realizó un estudio experimental de tipo prospectivo longitudinal con 12 Cavia porcellus distribuidos por igual en tres grupos: 2 experimentales que recibieron 0.5 ml y 1.0 ml de extracto de membrana de B. bacilliformis respectivamente y 1 grupo control que recibió 0.5 de suero salino fisiológico de los que se obtuvieron muestras de sangre periférica basal y un control a las 6, 24 y 48 horas del tratamiento que se sometieron a coloración Wright para el recuento linfocitario. Resultados: Se halló que el recuento linfocitario aumentó significativamente a las 24 horas de tratamiento (F ANVA=24.8607, p=0.0002) y se mantuvo a las 48 horas en los grupos experimentales (F ANVA=49.7903, p=0.0000), no hallándose diferencia significativa entre ambos grupos experimentales (α=0.05). Conclusiones: El extracto de membrana de B. bacilliformis aumenta la mitosis de linfocitosTesisTo evaluate the effect of Bartonella bacilliformis membrane extracts on the mitosis of Cavia porcellus lymphocytes. Methods: An experimental longitudinal prospective study was conducted with 12 Cavia porcellus distributed equally in three groups: 2 experimental groups that received 0.5 ml and 1.0 ml of membrane extract of B. bacilliformis respectively and 1 control group that received 0.5 of physiological saline from which samples of basal peripheral blood and a control at 6, 24 and 48 hours of the treatment that underwent Wright staining for the lymphocyte count. Results: It was found that the lymphocyte count increased significantly at 24 hours of treatment (F ANVA=24.8607, p = 0.0002) and was maintained at 48 hours in the experimental groups (F ANVA=49.7903, p = 0.0000), there was no significant difference between both experimental groups (α = 0.05). Conclusions: The membrane extract of B. bacilliformis increases lymphocyte mitosi

Topics: Extracto de membrana de bartonella bacilliformis, Bartonella bacilliformis, Mitosis de linfocitos T
Publisher: Universidad Nacional de Trujillo
Year: 2018
OAI identifier: oai:renati.sunedu.gob.pe:sunedu/615917
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