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Fruit, Vegetables, Dietary Fiber, and Risk of Colorectal Cancer

By Paul Terry, Edward Giovannucci, Karin B. Michels, Leif Bergkvist, Holger Hansen, Lars Holmberg and Alicja Wolk


Background: Several recent large prospective cohort studies have failed to demonstrate the presumed protective effect of fruit, vegetable, and dietary fiber consumption on colorectal cancer risk. To further explore this issue, we have examined these associations in a population that consumes relatively low amounts of fruit and vegetables and high amounts of cereals. Methods: We examined data obtained from a foodfrequency questionnaire used in a population-based prospective mammography screening study of women in central Sweden. Women with colorectal cancer diagnosed through December 31, 1998, were identified by linkage to regional cancer registries. Cox proportional hazards models were used to estimate relative risks. All statistical tests were twosided. Results: During an average 9.6 years of follow-up of 61 463 women, we observed 460 incident cases of colorecta

Year: 2013
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