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By I Shimon

Abstract

SSTR regulation of human fetal pituitary cells Figure 1 SSTR1 and SSTR2 expression in pituitary adenomas. RNA extracted from pituitary tumors was subjected to RNase protection assays using riboprobes for SSTR1 and SSTR2. N, non-functioning adenoma; A, GH-secreting tumor; P, PRL-secreting tumor; C, ACTH-secreting tumor. Adapted from Greenman & Melmed (1994b) � The Endocrine Society. Figure 2 SSTR5 expression in pituitary tumors. RNA extracted from pituitary tumors was subjected to RNase protection assay using riboprobe for SSTR5. N, non-functioning adenoma; A, GH-secreting tumor; P, PRL-secreting tumor. Adapted from Greenman & Melmed (1994a) � The Endocrine Society. Thus octreotide and lanreotide mediate their hormonal suppression in pituitary adenomatous cells through SSTR2 and possibly SSTR5, which bind these analogs with hig

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.321.6372
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