Glucose repressed the synthesis of 1,3-/?-glucanase in Neurospora crassa. The production of enzyme during growth in glucose-supplemented medium was negligible, but if deprived of carbon source the fungus actively synthesized high levels of enzyme when growth ceased. Similar results were obtained for 1,6-P-glucanase but less enzyme was produced. A different pattern of production of these enzymes was found in Trichoderma viride and Saccharomyces cerevisiae. The enzymes were produced in glucose-supplemented medium with increasing specific activity during growth. Resting cells deprived of glucose either failed to produce /?-glucanases or produced them in smaller quantities
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