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REVIEW Open Access Cellular and vaccine therapeutic approaches for gliomas

By Michelle J Hickey, Colin C Malone, Kate L Erickson, Martin R Jadus, Robert M Prins, Linda M Liau and Carol A Kruse


Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor. A small contingent of clinical researchers are focusing their efforts on testing the safety, feasibility and efficacy of experimental active and passive immunotherapy approaches for gliomas and are primarily conducting Phase I and II clinical trials. Few trials have advanced to the Phase III arena. Here we provide an overview of the cellular therapies and vaccine trials currently open for patient accrual obtained from a search o

Year: 2013
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