Twenty-six patients with advanced renal cell carcinoma were treated with suramin administered by continuous infusion, with dosing deter mined by a nomogram. One patient achieved a partial response and five patients achieved a minor response or had stable disease for>3 months. Toxicities included an immune-mediated thrombocytopenia in one pa tient and Staphylococcus sepsis that was not associated with neutropenia in five patients. Pharmacokinetic parameters were determined b
To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.