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Table 1 Lipase-catalyzed enantioselective hydrolyses: as Pseudomonas cepacia lipase = PCL Substrate Lipase Product Ee (%) Reference

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that contained both of the concepts “organic synthesis ” and “enzym- ” from 174 in 1993. It is not the intention of this review to comprehensively catalogue all biotransformations during this period but to instead describe selected highlights. We hope therefore that this review will act more as a primer or overview for this period. Many other good reviews have also covered parts of this period. 1–42 In particular the reviews of Stan Roberts have provided a wonderfully detailed review of 1996, 43 1997 44 and 1998. 45 More details of particular biotransformations can be found in several excellent specialized reviews that have appeared and these have been highlighted at the start of the relevant sections below. 2 Acyl transferases 2.1 Lipases Among the biocatalysts in organic synthesis, lipases are th

Year: 2013
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