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The Structure of Apo Human Glutamate Dehydrogenase Details Subunit Communication

By Allostery, Thomas J. Smith, Timothy Schmidt, Jie Fang, Jane Wu, Gary Siuzdak, Charles A. Stanley and Donald Danforth Plant

Abstract

Mammalian glutamate dehydrogenase (GDH) catalyzes the reversible oxidative deamination of L-glutamate to 2-oxoglutarate using NAD(P)(H) as coenzyme. The enzyme is a homohexamer an

Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.318.542
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