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Derivation of an aged mouse induced pluripotent stem cell line, IISHDOi005-A

By María del Carmen Ortuño-Costela, Victoria Cerrada, Marta García-López, Joaquín Arenas, Jesús Martínez, Alejandro Lucia, Rafael Garesse and M. Esther Gallardo

Abstract

A mouse iPSC line, IISHDOi005-A, generated from fibroblasts obtained from a mouse C57BL/6J with an age of 1 year and a half, has been obtained. For this purpose, reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.This work was supported by grants from: 1) the “Fondo de Investigación Sanitaria, Instituto de Salud Carlos III cofunded by FEDER funds”: PI13/00556 and PI16/00789 to RG, PI15/00484 and PI18/00151 to MEG and PI15/00558 to AL. 2) “Comunidad Autónoma de Madrid” (grant number S2010/BMD-2402 to RG. MdC.O-C receives grant support from the Ministerio de Educación, Cultura y Deporte (FPU16/03895). M.GL is supported by a grant from Instituto de Investigación Sanitaria Hospital 12 de Octubre, i+12. ME.G is supported by a “Miguel Servet” contract (CP16/00046) from Instituto de Salud Carlos III and FEDER funds.Peer reviewe

Publisher: 'Elsevier BV'
Year: 2019
DOI identifier: 10.1016/j.scr.2019.101418
OAI identifier: oai:digital.csic.es:10261/188722
Provided by: Digital.CSIC
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