In 2007, an outbreak of epizootic hemorrhagic disease (EHD) occurred in Turkey. On the basis of clinical investigation, 41 cattle were suspected to have EHD. Reverse transcription–PCR and sequence analyses indicated that the virus belonged to EHD virus serotype 6, thus confi rming EHD virus infection of cattle in Turkey. Epizootic hemorrhagic disease virus (EHDV) is a member of the genus Orbivirus, family Reoviridae, and is closely related to bluetongue virus (BTV). EHD often causes death in white-tailed deer and, less frequently, a bluetongue-like illness in cattle (1–3). Culicoides spp. act as vectors, transmitting EHDV between susceptible ruminant hosts (2). The clinical signs of EHD in cattle are fever, anorexia, dysphagia, ulcerative and necrotic lesions of the oral mucosa (Figure 1), hyperemia and edema of the conjunctival mucosae (Figure 2), sore muzzle, hyperemia of the teats and udder, hemorrhage, dehydration, and lameness (3). EHDV has been isolated from cattle throughout the world, including Africa, North America
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