Canine parvovirus (CPV), which causes hemorrhagic enteritis in dogs, has 3 antigenic variants: types 2a, 2b, and 2c. Molecular method assessment of the distribution of the CPV variants in Europe showed that the new variant CPV-2c is widespread in Europe and that the viruses are distributed in different countries. Canine parvovirus type 2 (CPV-2) is a small, nonenveloped DNA virus that emerged suddenly in 1978 as an enteric pathogen of dogs. Two antigenic variants, CPV-2a and CPV-2b, are now distributed worldwide (1). A third CPV variant, first named Glu-426 mutant and subsequently renamed CPV-2c, was detected in Italy in 2000 (2) and is now circulating in that country together with types 2a and 2b (3–5). The new variant 2c has also been reported in Vietnam by Nakamura et al., who developed monoclona
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