Location of Repository

References

By Clélia Gasquet, Eric M. Leroy, Tevi Benissan C, Nabias Rj, Trinh Ngoc, Leroy Em, Rouquet P, Formenty P, Souquière S, Kilbourne A and Froment J-m

Abstract

symptom onset, increased during the symptomatic period (as shown by higher titers on day 10), peaked by day 30 (2 weeks after recovery), then declined slowly over several years. Zaire ebolavirus IgG remained detectable, often at high levels,>11 years after the infection. These long-lasting IgG antibody responses found in 20 survivors of 3 different Zaire ebolavirus outbreaks rule out the hypothesis that low Ebola virus (and Marburg virus) seroprevalence rates found in epidemic regions of Africa are due to rapid loss of specific IgG. Whether this immunity is sufficient to protect from recurrent infection remains undetermined. These findings show that IgG ELISA is suitable for epidemiologic and epizootiologic investigations of Ebola and that Zaire ebolavirus IgG is an excellent indicator of Zaire ebolavirus circulation in humans

Topics: contacts, Kikwit, Democratic Republic of
Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.306.3596
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://citeseerx.ist.psu.edu/v... (external link)
  • http://wwwnc.cdc.gov/eid/artic... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.