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www.mdpi.com/journal/ijms Ribonucleoprotein Complexes That Control Circadian Clocks

By Dongni Wang, Xiaodi Liang, Xianyun Chen and Jinhu Guo

Abstract

Abstract: Circadian clocks are internal molecular time-keeping mechanisms that enable organisms to adjust their physiology and behavior to the daily surroundings. Misalignment of circadian clocks leads to both physiological and health impairment. Post-transcriptional regulation and translational regulation of circadian clocks have been extensively investigated. In addition, accumulating evidence has shed new light on the involvement of ribonucleoprotein complexes (RNPs) in the post-transcriptional regulation of circadian clocks. Numerous RNA-binding proteins (RBPs) and RNPs have been implicated in the post-transcriptional modification of circadian clock proteins in different model organisms. Herein, we summarize the advances in the current knowledge on the role of RNP complexes in circadian clock regulation

Topics: ribonucleoprotein, circadian clock, transcription, translation, post-transcription
Year: 2013
OAI identifier: oai:CiteSeerX.psu:10.1.1.297.9653
Provided by: CiteSeerX
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