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Impact of iron supplementation on schistosomiasis control in Zambian school children in a highly endemic area

By Victor Mwanakasale, Seter Siziya, James Mwansa, Artemis Koukounari and Alan Fenwick


Aim: To study im: S haematobium reinfection intensity was significantly lower in boys in the intervention group than in boys in the control group at 6 months (P<0.001) and 9 months (P<0.001) of supplementation. Significantly lower S haematobium reinfection intensity was found in girls in the intervention group than in girls in the control group only at 6 months of supplementation (P=0.018). Boys in the intervention group were 42% (Adjusted Risk Ratio =0.58, 95% confidence interval 0.39, 0.86) less likely to be reinfected with S haematobium than in the control group at 6 months follow up. pact of once weekly iron supplementation on praziquantel cure rate, Schistosoma haematobium reinfection, and haematological parameters in pupils aged between 9 and 15 years of age in Nchelenge district, Zambia. Methods: Pupils in the intervention group received once weekly dose of ferrous sulphate at 200mg while those in the control received once weekly vitamin C at 100mg for up to 9 months. Both study groups received a single dose of praziquantel at baseline. Results Conclusion: Once weekly iron supplementation can decrease S haematobium reinfection after 6 months and should be incorporated into school based schistosomiasis control programs in highly endemic areas

Topics: DT Africa, RA0421 Public health. Hygiene. Preventive Medicine
Publisher: College of Medicine, University of Malawi and Medical Association of Malawi
Year: 2009
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Provided by: LSE Research Online
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