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The CancerGrid Experience: Metadata-Based Model-Driven Engineering for Clinical Trials

By Jim Davies, Jeremy Gibbons, Steve Harris and Charles Crichton


The CancerGrid approach to software support for clinical trials is based on two principles: careful curation of semantic metadata about clinical observations, to enable subsequent data integration, and model-driven generation of trial-specific software artifacts from a trial protocol, to streamline the software development process. This paper explains the approach, presents four varied case studies, and discusses the lessons learned. Keywords: Metadata, ISO/IEC 11179, semantic frameworks, model-driven engineering, clinical informatics, electronic governmen

Year: 2012
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