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Biocompatible parylene neurocages developing a robust method for live neural network studies

By Angela Tooker, Ellis Meng, Jon Erickson, Yu-Chong Tai and Jerry Pine

Abstract

We present a refined method and design for fabricating parylene neurocages for in vitro studies of live neural networks. Parylene neurocages are biocompatible and very robust, making them ideally suited for studying the synaptic connections netween individual neurons to gain insight into learning and memory. The neurocage fabrication process is significantly less complex than earlier versions. Previous neurocage designs achieved limited neuronal outgrowth; however, the long-term cell survival rate was 50%

Topics: Caltech Library Services
Publisher: 'Institute of Electrical and Electronics Engineers (IEEE)'
Year: 2005
OAI identifier: oai:authors.library.caltech.edu:1650

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