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Low-dose oral interferon a possibly retards the progression of idiopathic pulmonary fibrosis and alleviates associated cough in some patients Idiopathic pulmonary fibrosis (IPF) has no effective treatment and a relatively short life expectancy after diagnosis. Interferon a (IFNa) inhibits the growth of proliferating fibroblasts. 1 IFNa also inhibits the production of collagen by fibroblasts independently of its effect on fibroblast replication. 2 Biological activity of low-dose IFNa by oromucosal administration has been reporte

Year: 2011
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