Location of Repository

MEDIA RELEASE IBN Develops Novel Injectable Hydrogel with Tunable Stiffness for Tissue Repair and Regeneration

By 

Abstract

institute, have developed the first injectable hydrogel system with variable stiffness that can control cell proliferation and differentiation in a two-dimensional (2D) and threedimensional (3D) cell culture environment. This unique hydrogel invention has important tissue engineering applications, especially in the treatment of neurological disorders, brain and muscle injuries 1. Human mesenchymal stem cells (hMSCs) are commonly used in cell therapies because they are easy to isolate and handle. hMSCs can differentiate into multiple cell types, such as osteoblasts (bone cells), neurons (nerve cells) and cardiac myocytes (heart muscle cells) via cell culture. The use of hydrogels as scaffolds for the cultivation of hMSCs is attractive because the former’s high water content matrix provides high permeability for oxygen, nutrients and other water-soluble metabolites. This quality makes them an excellent environment for cell growth and tissue regeneration. In addition, hydrogels can administer cells to the precise locations in the body for tissue repair and regeneration

Year: 2011
OAI identifier: oai:CiteSeerX.psu:10.1.1.186.6600
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://citeseerx.ist.psu.edu/v... (external link)
  • http://www.ibn.a-star.edu.sg/i... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.