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Notes Electrospinning of Bovine Serum Albumin. Optimization and the Use for Production of Biosensors.

By Tomasz Kowalczyk, Ra Nowicka, Danek Elbaum and Tomasz A. Kowalewski


Electrospinning of the globular protein, bovine serum albumin (BSA), was optimized to obtain proteinous fibers suitable as biosensors. It was shown that the as-spun protein preserves its native form, whereas solubility of the cross-linked in the ambient conditions BSA nanofibers evidently decreases. Insoluble BSA fibers can be easily modified to be used as two-dimensional biosensors. Here, we show the micro pH sensor obtained from the BSA fiber stained with a fluorescein derivative (FITC). 1

Year: 2008
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