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A Microfluidic System for the Capture and Expansion of Metastatic Cancer Cells

By Connor Michael Haley, Ian Maxwell Maitland, Stephen O. Petry and Stuart Scott Sundseth

Abstract

Understanding metastatic cancer cells is important to increasing the cancer survival rate. Microfluidic fabrication allows us to create diminutive environments to perform experiments on individual cells. This project was aimed at developing a design for a microfluidic device that has the potential to separate metastatic and non-metastatic cancer cells via chemotaxis through a hydrogel basement membrane mimic. The team’s device allows for the isolation and expansion of metastatic cancer cells within micron-sized wells for further analysis

Publisher: Digital WPI
Year: 2015
OAI identifier: oai:digitalcommons.wpi.edu:mqp-all-4988
Provided by: DigitalCommons@WPI

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