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Synthesis of Novel Materials Containing Catechol Bioisosteres

By Alexander Lee Trudeau and Christopher Henry Schuster

Abstract

The photoinitiated intramolecular ylide-alkene cycloaddition reaction which was developed in our laboratory provides a method for construction of up to three rings and six chiral centers in a single experimental operation from relatively simple starting materials. This project has attempted to utilize this reaction to quickly synthesize novel materials which incorporate catechol bioisosteres into the organic scaffold in the hopes of imparting potentially useful bio-activity to the new molecules

Publisher: Digital WPI
Year: 2008
OAI identifier: oai:digitalcommons.wpi.edu:mqp-all-2882
Provided by: DigitalCommons@WPI

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