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In-vitro Turbulence Mapping in Prosthetic Heart Valves using Generalized Phase-Contrast MRI

By P. Dyverfeldt, J-p. E. Kvitting, A. Sigfridsson, S. Franzén, A. F. Bolger and T. Ebbers

Abstract

Turbulence, characterized by velocity fluctuations, is a sign of suboptimal hemodynamics in prosthetic heart valves [1]. Turbulence causes pressure drops and exposes endothelial cells and blood constituents to abnormal stresses which can lead to blood trauma and promote the pathogenesis of atherosclerosis. Phase-contrast MRI (PC-MRI) has previously been shown to be valuable for the assessment of the mean velocity field around prosthetic heart valves [2]. In addition to mean velocity quantification by conventional velocity mapping, PC-MRI can be used to quantify turbulenc

Year: 2010
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