Hemodynamic Response to 1ms Stimulus is Detectable in Human Subjects


In a previous study, we have shown that in humans it is possible to detect blood oxygenation level dependent (BOLD) signal changes evoked by a visual stimulus presented only for 5 ms. Moreover, we observed that the extrapolated intercept at 0ms stimulus duration was not zero suggesting that below a specific stimulus duration the hemodynamic response remains constant. In this study, we have expanded our previous investigation on the temporal behavior of the BOLD response by zooming into the time scale of stimulus durations as short as 0,1 to 5ms (at 7T) and 1 to 5ms (at 3T), in order to evaluate if there is indeed a minimum hemodynamic response

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This paper was published in MPG.PuRe.

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