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Reviews and Overviews Risk-Benefit Decision Making for Treatment of Depression During Pregnancy

By Katherine L. Wisner, Deborah A. Zarin, Eric S. Holmboe, Alan J. Gelenberg, Henrietta L. Leonard and Ellen Frank Ph. D


Women of childbearing age frequently suffer from major depression. Estimates of the lifetime risk in community samples have varied from 10 % to 25%, with the peak prevalence between 25 and 44 years of age (1). Nine percent of pregnant women have illnesses that fulfill the Research Diagnostic Criteria for depression (2). In a large sample of childbearing-age women who sought treatment at an urban psychiatric hospital (3), the proportion whose illness had begun during pregnancy or within 3 months of birth was 9%. When the sample was restricted to women who had ever experienced a pregnancy, one out of seven women who sought care was experiencing an episode that began during pregnancy or the postpartum period. Many women have difficulty obtaining pharmacologic care during pregnancy. This problem was highlighted i

Topics: Psychiatric Association identified treatment
Year: 2009
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