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Development and Analysis of a Plate Based Diversity Set

By Jens Loesel


A full file HTS is the only way to cover all of a drug companies compound space in its entirety. For many purposes a full file HTS seems neither cost efficient nor necessary. The work described here investigates how much of the Pfizer compound space can be covered using a sub selection of existing plates. Based on this work a prioritised plate order has been proposed

Year: 2009
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