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Bootstrap Techniques in Physical Mapping

By Steffen Heberfunctional, Genome Analysis and Theoretical Bioinformatics


1 Introduction The goal of physical mapping by hybridization[7, 8, 4] is to order a library of cloned fragments of DNA according to their position in the genomeusing hybridization experiments. Physical maps are important tools for localization and isolationof genes, for exploring the organization and evolution of genomes, and for efficient sequencing

Year: 2009
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