“It is Clinicians need a simple, fast, reliable, and inexpensive way of identifying the evidence base relevant to their clinical practice. It is often believed that the only way to identify all relevant evidence is to perform hand-searches of the literature to supplement computer searches; this is complex and labor intensive. However, most of quality randomized controlled trials cited in systematic reviews in pain medicine are listed in computer databases. We performed two studies to investigate the efficiency—in terms of sensitivity, specificity, and precision—of three computer search strategies: Optimally Sensitive Search Strategy, which is used by the Cochrane Collaboration
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