Skip to main content
Article thumbnail
Location of Repository

An evolutionary trace method defines binding surfaces common to protein families

By Olivier Lichtarge, Henry R. Bourne and Fred E. Cohen


1Departments of Cellular and X-ray or NMR structures of proteins are often derived without their Molecular Pharmacology and ligands, and even when the structure of a full complex is available, the area Medicine and of contact that is functionally and energetically significant may be a 2Department of Pharmaceutical Chemistry specialized subset of the geometric interface deduced from the spatial University of California proximity between ligands. Thus, even after a structure is solved, it San Francisco remains a major theoretical and experimental goal to localize protei

Topics: SH2 domains, SH3 domains, functional motifs, protein
Year: 1996
OAI identifier: oai:CiteSeerX.psu:
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.