The goal of modern neurosurgery is to improve the survival rates and quality of life of patients with surgically treatable intracranial lesions. It is known, however, that tumor progression and survival in cases of malignant intracranial tumors is contingent on the extent of tumor removal. The protection of functions potentially at risk during surgery is facilitated by functional mapping of critical eloquent areas. The gold standards for mapping eloquent areas of the brain are invasive cortical stimulation and somatosensory evoked potential monitoring. A number of secondary physiological changes occur as a result of neuronal activity in the brain. Measurable changes such as glucose utilization led to the development of functional mapping with 18 FDG-PET. It was also found that another of these changes, local differences in oxyge

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