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Considering the cancer consequences of altered DNA polymerase function

By Thomas A Kunkel

Abstract

AbstractOur appreciation of the DNA transactions that replicate and maintain a stable human genome is changing rapidly due to recent discoveries indicating that eukaryotic cells contain many more DNA polymerases than previously thought. This review describes emerging information on the properties and functions of human DNA polymerases, with emphasis on connections between DNA polymerase functions and cancer

Publisher: Cell Press.
Year: 2003
DOI identifier: 10.1016/S1535-6108(03)00027-8
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