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the Most Compact Eukaryotic Genome, Shows an Excess of Introns in Highly Expressed Genes

By Lanier William, Moustafa Ahmed, Bhattacharya Debashish and Comeron Josep M.

Abstract

genome appears to be in opposition to simple explanations of genome evolution based on unidirectional tendencies, either neutral or selective. Therefore, patterns of intron retention in this species can potentially provide insights into the forces governing intron evolution. = <0.005).In a species with a genome that has been recently subjected to a great reduction of non-coding DNA, these results imply the existence of selective/functional roles for introns that are principally detectable in highly expressed genes. In these cases, introns are likely maintained by balancing the selective forces favoring their maintenance with other mutational and/or selective forces acting on genome size

Publisher: Public Library of Science
Year: 2008
DOI identifier: 10.1371/journal.pone.0002171
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